MIP antibody

Catalog No. ABIN7074547

Product Details anti-MIP Antibody

Target: MIP (Major Intrinsic Protein of Lens Fiber (MIP))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MIP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Mouse, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Human AQP0

Application Details

Application Notes: WB (M,R) 1:1000-1:3000, IHC/IF (M,R) 1:200-1:600/1:300-1:600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for MIP

Target: MIP (Major Intrinsic Protein of Lens Fiber (MIP))

Alternative Name: AQP0 (MIP Products)

Background: Aquaporin 0 or MIP26 (major intrinsic protein 26kD), and Aquaporin 1 has been the foundation of the growing family of aquaporins. The lens specific Aquaporin 0 represents up to 80 % of total lens membrane protein. Defects in Aquaporin 0 are a cause of autosomal recessive congenital cataract. The lens opacity mutation (LOP) is an AA substitution that inhibits targeting of MIP to the cell membrane. Human Aquaporin 0 is a 263 amino acid transmembrane protein belonging to the MIP family. Aquaporin families of proteins are predicted to contain six transmembrane domains.

Molecular Weight: 28 kDa

Gene ID: 17339

NCBI Accession: NP_036196

UniProt: P30301