Ly6g antibody

Catalog No. ABIN7074524

Product Details anti-Ly6g Antibody

Target: Ly6g (Lymphocyte Antigen 6 Complex, Locus G (Ly6g))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ly6g antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse Ly6g

Application Details

Application Notes: IHC/IF (M,R) 1:300-1:1000/1:200-1:600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-Ly6g antibody (ABIN7074524)

Wang, Zhang, Shao, Zhuang, Sui, Liu, Chen, Hou, Kong, Liu, Zheng, Liu, Chen, Zhang, Jia, Gao: "TRIM31 facilitates K27-linked polyubiquitination of SYK to regulate antifungal immunity." in: Signal transduction and targeted therapy, Vol. 6, Issue 1, pp. 298, (2022) (PubMed).

Hu, Peng, Jiang, Li, Su, Zhang, Li, Song, Cheng, Xia, Wu: "Metformin as a senostatic drug enhances the anticancer efficacy of CDK4/6 inhibitor in head and neck squamous cell carcinoma." in: Cell death & disease, Vol. 11, Issue 10, pp. 925, (2021) (PubMed).

Liu, Lan, Mo, Yang, Wei, Wei: "Antitumor and Radiosensitization Effects of a CXCR2 Inhibitor in Nasopharyngeal Carcinoma." in: Frontiers in cell and developmental biology, Vol. 9, pp. 689613, (2021) (PubMed).

Zhang, Guo, Zhou, Wang, Liu, Wu, Ding: "OX40 agonist combined with irreversible electroporation synergistically eradicates established tumors and drives systemic antitumor immune response in a syngeneic pancreatic cancer model." in: American journal of cancer research, Vol. 11, Issue 6, pp. 2782-2801, (2021) (PubMed).

Yang, Song, Wang, Liu, Wu, Duan, Zhang, Bi, Geng, Chen, Zhu: "Daphnetin ameliorates acute lung injury in mice with severe acute pancreatitis by inhibiting the JAK2-STAT3 pathway." in: Scientific reports, Vol. 11, Issue 1, pp. 11491, (2021) (PubMed).

Jiang, Li, Luo, Jiang, Zhang, Yang, Chen: "Emodin ameliorates acute pancreatitis-induced lung injury by suppressing NLRP3 inflammasome-mediated neutrophil recruitment." in: Experimental and therapeutic medicine, Vol. 22, Issue 2, pp. 857, (2021) (PubMed).

Qie, Jiang, Liu, Hu, Chen, Xie, Liu: "Single-cell RNA-Seq reveals the transcriptional landscape and heterogeneity of skin macrophages in Vsir-/- murine psoriasis." in: Theranostics, Vol. 10, Issue 23, pp. 10483-10497, (2021) (PubMed).

Yang, Zhao, Zhu, Hu, Wang, Zang, Jin, Bi, Huang, Liu, Li, Yin, Li: "Tumor Temporal Proteome Profiling Reveals the Immunological Triple Offensive Induced by Synthetic Anti-Cancer Salmonella." in: Frontiers in immunology, Vol. 12, pp. 712936, (2021) (PubMed).

Zhao, Zhang, Xu, Wang, Li: "Selective Loss of Brain-Derived Neurotrophic Factor Exacerbates Brain Injury by Enhancing Neuroinflammation in Experimental Streptococcus pneumoniae Meningitis." in: Frontiers in immunology, Vol. 11, pp. 1357, (2021) (PubMed).

Wang, Yang, Li, Zhang, Pan, Su, Chen, Li, Qiu, Huang: "CD62Ldim Neutrophils Specifically Migrate to the Lung and Participate in the Formation of the Pre-Metastatic Niche of Breast Cancer." in: Frontiers in oncology, Vol. 10, pp. 540484, (2020) (PubMed).

Target Details for Ly6g

Target: Ly6g (Lymphocyte Antigen 6 Complex, Locus G (Ly6g))

Alternative Name: Ly6g (Ly6g Products)

Synonyms: Gr-1 antibody, Gr1 antibody, Ly-6G antibody, lymphocyte antigen 6 complex, locus G antibody, Ly6g antibody

Background: Ly6G is a GPI-anchored protein, that is also known as the myeloid differentiation antigen Gr1. The antigen is transiently expressed on monocytes in the bone marrow. The level of antigen expression in the bone marrow directly correlates with granulocyte differentiation and maturation. Ly6G is expressed predominantly on neutrophils, also in a subset of eosinophils, differentiating pre-monocytes, and plasmacytoid dendritic cells.

Gene ID: 546644

NCBI Accession: NP_001297367

UniProt: P35461