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KIF5B antibody

KIF5B Reactivity: Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7074440
  • Target See all KIF5B Antibodies
    KIF5B (Kinesin Family Member 5B (KIF5B))
    Reactivity
    • 36
    • 19
    • 12
    • 8
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 31
    • 7
    • 2
    Rabbit
    Clonality
    • 32
    • 8
    Polyclonal
    Conjugate
    • 30
    • 3
    • 3
    • 2
    • 1
    • 1
    This KIF5B antibody is un-conjugated
    Application
    • 34
    • 17
    • 15
    • 9
    • 6
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Rat
    Purification
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to Mouse KIF5B
  • Application Notes
    WB (M,R) 1:2000-1:4000, IHC/IF (M,R) 1:500-1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    KIF5B (Kinesin Family Member 5B (KIF5B))
    Alternative Name
    KIF5B (KIF5B Products)
    Background
    Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. May be involved in the mechanisms of growth arrest induced by exposure to DNA-damaging drugs or by cellular senescence . Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner . Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation .
    Molecular Weight
    130 kDa
    Gene ID
    16573
    NCBI Accession
    NP_032474
    UniProt
    Q61768
    Pathways
    Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization
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