KIF5B antibody
-
- Target See all KIF5B Antibodies
- KIF5B (Kinesin Family Member 5B (KIF5B))
-
Reactivity
- Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This KIF5B antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Rat
- Purification
- Affinity purification
- Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse KIF5B
-
-
- Application Notes
- WB (M,R) 1:2000-1:4000, IHC/IF (M,R) 1:500-1:1000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
-
- Target
- KIF5B (Kinesin Family Member 5B (KIF5B))
- Alternative Name
- KIF5B (KIF5B Products)
- Background
- Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. May be involved in the mechanisms of growth arrest induced by exposure to DNA-damaging drugs or by cellular senescence . Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner . Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation .
- Molecular Weight
- 130 kDa
- Gene ID
- 16573
- NCBI Accession
- NP_032474
- UniProt
- Q61768
- Pathways
- Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization
-