KIF5B antibody
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- Target See all KIF5B Antibodies
- KIF5B (Kinesin Family Member 5B (KIF5B))
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KIF5B antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Rat
- Purification
- Affinity purification
- Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse KIF5B
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- Application Notes
- WB (M,R) 1:2000-1:4000, IHC/IF (M,R) 1:500-1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- KIF5B (Kinesin Family Member 5B (KIF5B))
- Alternative Name
- KIF5B (KIF5B Products)
- Synonyms
- KINH antibody, KNS antibody, KNS1 antibody, UKHC antibody, Khc antibody, AL022807 antibody, Khcs antibody, Kns1 antibody, Ukhc antibody, khc antibody, KIF5A antibody, kinesin family member 5B antibody, kinesin heavy chain antibody, kinesin-1 antibody, kinesin-1 heavy chain antibody, kinesin family member 5B S homeolog antibody, KIF5B antibody, LOC411769 antibody, cgd6_2790 antibody, kin-1 antibody, Tb927.1.1350 antibody, LACBIDRAFT_305999 antibody, Khc antibody, LOC100538629 antibody, Kif5b antibody, kif5b.S antibody
- Background
- Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. May be involved in the mechanisms of growth arrest induced by exposure to DNA-damaging drugs or by cellular senescence . Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner . Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation .
- Molecular Weight
- 130 kDa
- Gene ID
- 16573
- NCBI Accession
- NP_032474
- UniProt
- Q61768
- Pathways
- Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization
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