KDELR3 antibody

Catalog No. ABIN7074401

Product Details anti-KDELR3 Antibody

Target: KDELR3 (kDELR3) (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 3 (kDELR3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDELR3 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse KDELR3

Application Details

Application Notes: WB (H,M,R) 1:2000-1:4000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for KDELR3

Target: KDELR3 (kDELR3) (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 3 (kDELR3))

Alternative Name: KDELR3 (kDELR3 Products)

Synonyms: ERD2L3 antibody, AI173274 antibody, ERD2 antibody, kdelr antibody, KDEL endoplasmic reticulum protein retention receptor 3 antibody, KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 antibody, KDEL endoplasmic reticulum protein retention receptor 3 L homeolog antibody, KDELR3 antibody, Kdelr3 antibody, kdelr3.L antibody

Background: This gene encodes a member of the KDEL endoplasmic reticulum protein retention receptor family. Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. KDELR3 was the third member of the family to be identified. Alternate splicing results in multiple transcript variants.

Molecular Weight: 28 kDa

Gene ID: 105785

NCBI Accession: NP_598851

UniProt: Q8R1L4

Pathways: ER-Nucleus Signaling, Maintenance of Protein Location