IL23R antibody

Catalog No. ABIN7074355

Product Details anti-IL23R Antibody

Target: IL23R (Interleukin 23 Receptor (IL23R))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL23R antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse IL-23R

Application Details

Application Notes: IHC/IF (M,R) 1:200-1:400/1:100-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for IL23R

Target: IL23R (Interleukin 23 Receptor (IL23R))

Alternative Name: IL-23R (IL23R Products)

Synonyms: IL-23R antibody, IL23R antibody, il-23r antibody, interleukin 23 receptor antibody, IL23R antibody, il23r antibody, Il23r antibody

Background: Interleukin-23 receptor is a type I cytokine receptor which is a subunit of the receptor for IL-23. This protein pairs with the receptor molecule IL-12Rβ1 (IL12RB1), together forming the IL-23 receptor complex, and both are required for IL-23 signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.

Gene ID: 209590

NCBI Accession: NP_653131

UniProt: Q8K4B4

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation