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CD51 antibody

ITGAV Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7074314
  • Target See all CD51 (ITGAV) Antibodies
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    Reactivity
    • 93
    • 51
    • 22
    • 7
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 64
    • 30
    • 9
    Rabbit
    Clonality
    • 57
    • 45
    Polyclonal
    Conjugate
    • 54
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD51 antibody is un-conjugated
    Application
    • 47
    • 46
    • 29
    • 26
    • 21
    • 14
    • 14
    • 13
    • 10
    • 9
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Rat
    Purification
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to Mouse Integrin alpha-V
    Top Product
    Discover our top product ITGAV Primary Antibody
  • Application Notes
    IHC/IF (H,M,R) 1:500-1:2000/1:500-1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    CD51 (ITGAV) (Integrin alpha V (ITGAV))
    Alternative Name
    Integrin alpha V (ITGAV Products)
    Synonyms
    1110004F14Rik antibody, 2610028E01Rik antibody, CD51 antibody, D430040G12Rik antibody, MSK8 antibody, VNRA antibody, VTNR antibody, Cd51 antibody, integrin subunit alpha V antibody, integrin alpha V antibody, ITGAV antibody, Itgav antibody
    Background
    The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling . ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling . ITGAV:ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV:ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1.
    Gene ID
    16410
    NCBI Accession
    NP_032428
    UniProt
    P43406
    Pathways
    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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