IP3 Receptor antibody

Catalog No. ABIN7074293

Product Details anti-IP3 Receptor Antibody

Target: IP3 Receptor (ITP-R83A) (Inositol 1,4,5,-Tris-Phosphate Receptor (ITP-R83A))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IP3 Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Mouse, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Human IP3 receptor

Application Details

Application Notes: WB (H) 1: 500-1: 1000, IHC/IF (M,R) 1:500-1:1500/1:750-1:1500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for IP3 Receptor

Target: IP3 Receptor (ITP-R83A) (Inositol 1,4,5,-Tris-Phosphate Receptor (ITP-R83A))

Alternative Name: IP3 receptor (ITP-R83A Products)

Background: Inositol 1,4,5-trisphosphate receptor type 1 is a protein that in humans is encoded by the ITPR1 gene. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

Molecular Weight: 313 kDa

Gene ID: 3708

NCBI Accession: NP_001093422

UniProt: Q14643

Pathways: Fc-epsilon Receptor Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma