HLA-DOA antibody

Catalog No. ABIN7074244

Product Details anti-HLA-DOA Antibody

Target: HLA-DOA (HLA Class II DO alpha (HLA-DOA))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HLA-DOA antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Human HLA-DOA

Application Details

Application Notes: WB (M) 1:500-1:1500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for HLA-DOA

Target: HLA-DOA (HLA Class II DO alpha (HLA-DOA))

Alternative Name: HLA-DOA (HLA-DOA Products)

Synonyms: HLA-DNA antibody, HLA-DZA antibody, HLADZ antibody, major histocompatibility complex, class II, DO alpha antibody, HLA-DOA antibody

Background: HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

Molecular Weight: 35 kDa

Gene ID: 3111

NCBI Accession: NP_002110

UniProt: P06340

Pathways: Human Leukocyte Antigen (HLA) in Adaptive Immune Response