HSPD1 antibody
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- Target See all HSPD1 Antibodies
- HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HSPD1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoelectron Microscopy (IEM)
- Cross-Reactivity
- Human, Rat
- Purification
- Affinity purification
- Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse HSP60
- Top Product
- Discover our top product HSPD1 Primary Antibody
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- Application Notes
- WB (H,M,R) 1:3000-1:10000, IHC/IF ,IEM (H,M,R) 1:500-1:1000/1:500-1:1000/1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))
- Alternative Name
- Hsp60 (HSPD1 Products)
- Background
- Heat shock protein 60 (HSP60) is a mitochondrial chaperonin that is typically held responsible for the transportation and refolding of proteins from the cytoplasm into the mitochondrial matrix. In addition to its role as a heat shock protein, HSP60 functions as a chaperonin to assist in folding linear amino acid chains into their respective three-dimensional structure. Through the extensive study of groEL, HSP60's bacterial homolog, HSP60 has been deemed essential in the synthesis and transportation of essential mitochondrial proteins from the cell's cytoplasm into the mitochondrial matrix. Further studies have linked HSP60 to diabetes, stress response, cancer and certain types of immunological disorders.
- Molecular Weight
- 60 kDa
- Gene ID
- 15510
- NCBI Accession
- NP_034607
- UniProt
- P63038
- Pathways
- Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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