EIF3D antibody

Catalog No. ABIN7073884

Product Details anti-EIF3D Antibody

Target: EIF3D (Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF3D antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse EIF3D

Application Details

Application Notes: WB (H,M,R) 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for EIF3D

Target: EIF3D (Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D))

Alternative Name: EIF3D (EIF3D Products)

Synonyms: eif3s7 antibody, eIF3d antibody, DDBDRAFT_0217568 antibody, DDBDRAFT_0219927 antibody, DDB_0217568 antibody, DDB_0219927 antibody, EIF3S7 antibody, An15g03780 antibody, AO090026000811 antibody, eIF3-p66 antibody, eIF3-zeta antibody, 66/67kDa antibody, AA407891 antibody, Eif3s7 antibody, eIF3p66 antibody, wu:fb12a03 antibody, zgc:64097 antibody, eukaryotic translation initiation factor 3 subunit D antibody, eukaryotic translation initiation factor 3 subunit 7 antibody, eukaryotic initiation factor antibody, eIF-3 zeta antibody, eukaryotic translation initiation factor 3, subunit D antibody, translation initiation factor eIF-3 subunit 7 antibody, eukaryotic translation initiation factor 3 subunit D S homeolog antibody, Eukaryotic translation initiation factor 3 subunit D antibody, eif3d antibody, EIF3D antibody, eIF3-S7 antibody, ANI_1_540134 antibody, AOR_1_1456014 antibody, PTRG_07832 antibody, VDBG_06053 antibody, PGTG_10613 antibody, Tsp_00484 antibody, Eif3d antibody, eif3d.S antibody, eif-3.D antibody

Background: EIF3D is a protein belonging to the largest of the eukaryotic translation initiation factor family, eukaryotic translation initiation factor-3 (eIF3). eIF3 is a multiprotein complex composed of at least 13 different subunits. eIF3D binds to the 40S ribosomal subunit and thus helps in maintaining the 40S and 60S ribosomal subunits in a dissociated state. An important role of eIF3D is the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and promotes mRNA binding. eIF3D is the major RNA binding subunit of the eIF3 complex. It associates with the subunit p170 of eIF-3. Ubiquitous expression of eIF3D is seen in most of the tissues and it is phosphorylated upon DNA damage, likely by ATM or ATR.

Molecular Weight: 64 kDa

Gene ID: 55944

NCBI Accession: NP_061219

UniProt: O70194

Pathways: Ribonucleoprotein Complex Subunit Organization