CCDC111 antibody

Catalog No. ABIN7073534

Product Details anti-CCDC111 Antibody

Target: CCDC111 (Coiled-Coil Domain Containing 111 (CCDC111))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC111 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting (WB)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse CCDC111

Application Details

Application Notes: WB (M,R) 1:500-1:1000, IHC/IF (H) 1:700-1:1400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CCDC111

Target: CCDC111 (Coiled-Coil Domain Containing 111 (CCDC111))

Alternative Name: Coiled-coil domain-containing protein 111 (CCDC111 Products)

Synonyms: BC065112 antibody, primase and DNA directed polymerase antibody, primase and polymerase (DNA-directed) antibody, PRIMPOL antibody, Primpol antibody

Background: DNA primase and DNA polymerase required to tolerate replication-stalling lesions by bypassing them . Required to facilitate mitochondrial and nuclear replication fork progression by initiating de novo DNA synthesis using dNTPs and acting as an error-prone DNA polymerase able to bypass certain DNA lesions (By similarity). Shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA .

Molecular Weight: 64 kDa

Gene ID: 408022

NCBI Accession: NP_001001184

UniProt: Q6P1E7