CCR6 antibody

Catalog No. ABIN7073457

Product Details anti-CCR6 Antibody

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR6 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Human CCR6

Application Details

Application Notes: WB (H,M,R) 1:1000-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CCR6

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Alternative Name: CCR6 (CCR6 Products)

Synonyms: BN-1 antibody, C-C CKR-6 antibody, CC-CKR-6 antibody, CCR-6 antibody, CD196 antibody, CKR-L3 antibody, CKRL3 antibody, CMKBR6 antibody, DCR2 antibody, DRY6 antibody, GPR29 antibody, GPRCY4 antibody, STRL22 antibody, Cmkbr6 antibody, KY411 antibody, C-C motif chemokine receptor 6 antibody, chemokine (C-C motif) receptor 6 antibody, CCR6 antibody, Ccr6 antibody

Background: Chemokine receptor 6 also known as CCR6 is a CC chemokine receptor protein which in humans is encoded by the CCR6 gene. CCR6 has also recently been designated CD196 (cluster of differentiation 196). This protein belongs to family A of G protein-coupled receptor superfamily. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dendritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.

Molecular Weight: 42 kDa

Gene ID: 12458

NCBI Accession: NP_004358

UniProt: P51684

Pathways: cAMP Metabolic Process