CHMP1A antibody

Catalog No. ABIN7073439

Product Details anti-CHMP1A Antibody

Target: CHMP1A (Charged Multivesicular Body Protein 1A (CHMP1A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP1A antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse CHMP1a

Application Details

Application Notes: WB (H,M,R) 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CHMP1A

Target: CHMP1A (Charged Multivesicular Body Protein 1A (CHMP1A))

Alternative Name: CHMP1a (CHMP1A Products)

Synonyms: CHMP1 antibody, PCH8 antibody, PCOLN3 antibody, PRSM1 antibody, VPS46-1 antibody, VPS46A antibody, 2900018H07Rik antibody, Pcoln3 antibody, charged multivesicular body protein 1A antibody, CHMP1A antibody, Chmp1a antibody

Background: Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. May also be involved in chromosome condensation. Targets the Polycomb group (PcG) protein PCGF4/BMI1 to regions of condensed chromatin. May play a role in stable cell cycle progression and in PcG gene silencing.

Molecular Weight: 27 kDa

Gene ID: 234852

NCBI Accession: NP_663581

UniProt: Q921W0