LASS4 antibody

Catalog No. ABIN7073433

Product Details anti-LASS4 Antibody

Target: LASS4 (CERS4) (Ceramide Synthase 4 (CERS4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LASS4 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse LASS4

Application Details

Application Notes: WB (H,M,R) 1:500- 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for LASS4

Target: LASS4 (CERS4) (Ceramide Synthase 4 (CERS4))

Alternative Name: LASS4 (CERS4 Products)

Background: LASS4 is a member of the LASS (longevity assurance homologue) family which are involved in determining life span in yeast, by an unknown molecular mechanism. Members of this family are highly conserved from yeasts to mammals.LASS proteins are thought to be involved in ceramide synthesis. Overproduction of a single LASS protein results in an increase in one or more specific ceramide species, which differ in fatty-acid chain length. LASS proteins possess specific fatty acyl-CoA preferences, but all can use sphingosine or dihydrosphingosine as the long-chain base substrate. LASS family members exhibit different tissue-specific expression patterns, which may contribute to the production of tissue-specific ceramides.

Molecular Weight: 46 kDa

Gene ID: 67260

NCBI Accession: NP_080334

UniProt: Q9D6J1