ANP32B antibody

Catalog No. ABIN7072887

Product Details anti-ANP32B Antibody

Target: ANP32B (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member B (ANP32B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANP32B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse PHAPI2 / APRIL

Application Details

Application Notes: WB (H) 1:500-1:1000, IHC/IF (M,R) 1:600-1:1200/1:300-1:600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ANP32B

Target: ANP32B (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member B (ANP32B))

Alternative Name: PHAPI2 / APRIL (ANP32B Products)

Synonyms: APRIL antibody, PHAPI2 antibody, SSP29 antibody, 2410015B15Rik antibody, PAL31 antibody, PHAPI2a antibody, Ssp29 antibody, cb908 antibody, fa99a11 antibody, wu:fa28c10 antibody, wu:fa99a11 antibody, wu:fb40e12 antibody, zgc:77745 antibody, hLAMP-1 antibody, MGC80871 antibody, ANP32B antibody, MGC69373 antibody, SLAN antibody, acidic nuclear phosphoprotein 32 family member B antibody, acidic (leucine-rich) nuclear phosphoprotein 32 family, member B antibody, acidic nuclear phosphoprotein 32 family member B L homeolog antibody, acidic leucine-rich nuclear phosphoprotein 32 family member B antibody, ANP32B antibody, Anp32b antibody, anp32b antibody, anp32b.L antibody, LOC494442 antibody

Background: ANP32B is a member of the highly conserved acidic leucine-rich nuclear phosphoprotein 32 (ANP32) family. The ANP32 proteins have been implicated in a broad array of physiological processes, including cell differentiation, apoptotic cell death, and cell proliferation. ANP32B was identified as a novel direct substrate for caspase-3 and acted as a negative regulator for leukemic cell apoptosis. ANP32B controls the expression of the dendritic cell maturation factor CD83 by regulating the transport of its mRNA to the cytoplasm. It also modulates the activity of the transcription factor Kruppel-like factor 5 (KLF5).

Molecular Weight: 31 kDa

Gene ID: 67628

NCBI Accession: NP_570959

UniProt: Q9EST5