Seladin 1 antibody
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- Target See all Seladin 1 (DHCR24) Antibodies
- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Seladin 1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human, Rat
- Purification
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse Seladin 1
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- Application Notes
- WB (H) 1:500-1:1000, IHC/IF (M,R) 1:600-1:3000/1:500-1:1300
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
- Alternative Name
- Seladin 1 (DHCR24 Products)
- Synonyms
- MGC82737 antibody, zgc:101638 antibody, DCE antibody, Nbla03646 antibody, SELADIN1 antibody, seladin-1 antibody, 2310076D10Rik antibody, 5830417J06Rik antibody, mKIAA0018 antibody, 24-dehydrocholesterol reductase antibody, 24-dehydrocholesterol reductase S homeolog antibody, delta(24)-sterol reductase antibody, DHCR24 antibody, dhcr24.S antibody, dhcr24 antibody, LOC5575872 antibody, CpipJ_CPIJ000670 antibody, Dhcr24 antibody
- Background
- The Seladin 1 encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. Protects cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis.Missense mutations in this gene have been associated with desmosterolosis.
- Molecular Weight
- 60 kDa
- Gene ID
- 74754
- NCBI Accession
- NP_444502
- UniProt
- Q8VCH6
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