Recombinant PRDM9 antibody

Catalog No. ABIN7072701

Product Details anti-PRDM9 Antibody

Target: PRDM9 (PR Domain Containing 9 (PRDM9))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This PRDM9 antibody is un-conjugated

Application: ELISA, Chromatin Immunoprecipitation (ChIP), Immunofluorescence (IF), Mass Spectrometry (MS)

Purpose: Anti-PRDM9 [RAB-C370], Rabbit IgG, kappa

Specificity: This antibody recognizes PRDM9 (Histone-lysine N-methyltransferase PRDM9). It binds to a folded domain, amino acids 195-385. PRDM9 is a histone methyltransferase that plays a key role in meiotic prophase by determining hotspot localization thereby promoting meiotic recombination.

Characteristics:

Original Species of Ab: Human

Original Format of Ab: Fab

Purification: Protein A affinity purified

Immunogen: This antibody was obtained by recombinant antibody (rAb) phage display recognizing PRDM9 protein under non-denaturing conditions.

Clone: RAB-C370

Isotype: IgG kappa

Application Details

Application Notes: This antibody has been used and recommended for the following methods: ELISA, IF, IP-MS, ChIP.

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for PRDM9

Target: PRDM9 (PR Domain Containing 9 (PRDM9))

Alternative Name: PRDM9 (PRDM9 Products)

Background: Histone-lysine N-methyltransferase PRDM9, PR domain-containing protein 9, PR domain zinc finger protein 9, Protein-lysine N-methyltransferase PRDM9, [histone H3]-lysine36 N-trimethyltransferase PRDM9, [histone H3]-lysine4 N-trimethyltransferase PRDM9, [histone H3]-lysine9 N-trimethyltransferase PRDM9, [histone H4]-N-methyl-L-lysine20 N-methyltransferase PRDM9, [histone H4]-lysine20 N-methyltransferase PRDM9, EC:2.1.1.-, anti-PRDM9-RAB-C370, PRDM9-A003-1459

UniProt: Q9NQV7