Recombinant CCR9 antibody (N-Term)
-
- Target See all CCR9 Antibodies
- CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))
- Antibody Type
- Recombinant Antibody
-
Binding Specificity
- N-Term
-
Reactivity
- Mouse
-
Host
- Rabbit
-
Clonality
- Chimeric
-
Conjugate
- This CCR9 antibody is un-conjugated
-
Application
- Flow Cytometry (FACS), Neutralization (Neut)
- Purpose
- Anti-CCR9 [9B1], Rabbit IgG, kappa
- Specificity
- 9B1 antibody recognizes CCR9 at the N-terminus. CCR9 is a member of the G protein coupled receptor family and is involved in T cell development in the thymus and in gut-associated immune response. Mouse CCR9 is highly expressed on different stages of thymocytes and upregulated on CD4+CD8+ cells.
- Characteristics
-
Original Species of Ab: Rat
Original Format of Ab: IgG2a
- Purification
- Protein A affinity purified
- Immunogen
- This antibody was raised by immunizing rats with KLH-conjugated linear peptide corresponding to the N-terminus of mouse CCR9.
- Clone
- 9B1
- Isotype
- IgG kappa
- Top Product
- Discover our top product CCR9 Primary Antibody
-
-
- Application Notes
- This antibody is recommended for the detection and analysis of CCR9 via flow cytometry (Farazuddin et al., 2019). Furthermore, it was demonstrated that this 9B1 antibody was capable of neutralizing CCR9 function, as it inhibited CCL25-induced calcium mobilization in L1.2-CCR9 cells (Rivera-Nieves et al., 2006).
- Comment
-
This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
- Restrictions
- For Research Use only
-
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
- Target
- CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))
- Alternative Name
- CCR9 (CCR9 Products)
- Background
- CD199, C-C chemokine receptor type 9, C-C CKR-9, CC-CKR-9, CCR-9, G-protein coupled receptor 28, GPR-9-6, CDw199, 9B-1
- UniProt
- Q9WUT7
-