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Recombinant CCR5 antibody (pSer337)

CCR5 Reactivity: Human WB, ELISA, FACS, IF, IP Host: Rabbit Chimeric V14-2 unconjugated Recombinant Antibody
Catalog No. ABIN7072658
  • Target See all CCR5 Antibodies
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    Antibody Type
    Recombinant Antibody
    Binding Specificity
    • 16
    • 13
    • 9
    • 8
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer337
    Reactivity
    • 138
    • 44
    • 36
    • 9
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 98
    • 33
    • 14
    • 2
    • 1
    Rabbit
    Clonality
    • 99
    • 45
    • 2
    Chimeric
    Conjugate
    • 80
    • 13
    • 9
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCR5 antibody is un-conjugated
    Application
    • 84
    • 62
    • 59
    • 23
    • 19
    • 15
    • 14
    • 13
    • 13
    • 13
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)
    Purpose
    Anti-CCR5 (phosphoserine 337) [V14/2], Rabbit IgG, kappa
    Specificity
    V14/2 antibody has been demonstrated to exclusively recognise CCR5 (CD195) phosphorylated at Ser 337.
    Characteristics

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2b

    Purification
    Protein A affinity purified
    Immunogen
    This antibody was raised by immunizing mice with a synthetic phospho peptide corresponding to the C-Terminal region of human CCR5 conjugated to BSA.
    Clone
    V14-2
    Isotype
    IgG kappa
    Top Product
    Discover our top product CCR5 Primary Antibody
  • Application Notes
    The V14/2 antibody is recommended for the specific detection and analysis of CCR5 phosphorylated on serine 337 (Pollok-Kopp et al., 2003). It was used in the detection of pS337 CCR5 in lysates of RBL-2H3 cells via Western blot (Pollok-Kopp et al., 2003). With other anti-CCR5 antibodies which react with nonphosporylated CCR5 (Ab01577) or CCR5 phosphorylated on different serine residues (Ab01578), it can be used to study dynamic regulation of CCR5 and of phosphorylation mechanisms.
    Comment

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.

    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % Proclin 300.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target
    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
    Alternative Name
    CCR5 (CCR5 Products)
    Background
    CD195, C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CHEMR13, HIV-1 fusion coreceptor, p337, pS337, Ser-337, Ser337
    UniProt
    P51681
    Pathways
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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