Recombinant CCR5 antibody (pSer337)
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- Target See all CCR5 Antibodies
- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
- Antibody Type
- Recombinant Antibody
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Binding Specificity
- pSer337
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Chimeric
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Conjugate
- This CCR5 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)
- Purpose
- Anti-CCR5 (phosphoserine 337) [V14/2], Rabbit IgG, kappa
- Specificity
- V14/2 antibody has been demonstrated to exclusively recognise CCR5 (CD195) phosphorylated at Ser 337.
- Characteristics
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Original Species of Ab: Mouse
Original Format of Ab: IgG2b
- Purification
- Protein A affinity purified
- Immunogen
- This antibody was raised by immunizing mice with a synthetic phospho peptide corresponding to the C-Terminal region of human CCR5 conjugated to BSA.
- Clone
- V14-2
- Isotype
- IgG kappa
- Top Product
- Discover our top product CCR5 Primary Antibody
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- Application Notes
- The V14/2 antibody is recommended for the specific detection and analysis of CCR5 phosphorylated on serine 337 (Pollok-Kopp et al., 2003). It was used in the detection of pS337 CCR5 in lysates of RBL-2H3 cells via Western blot (Pollok-Kopp et al., 2003). With other anti-CCR5 antibodies which react with nonphosporylated CCR5 (Ab01577) or CCR5 phosphorylated on different serine residues (Ab01578), it can be used to study dynamic regulation of CCR5 and of phosphorylation mechanisms.
- Comment
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))
- Alternative Name
- CCR5 (CCR5 Products)
- Background
- CD195, C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CHEMR13, HIV-1 fusion coreceptor, p337, pS337, Ser-337, Ser337
- UniProt
- P51681
- Pathways
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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