Recombinant TNFSF9 antibody

Catalog No. ABIN7072428

Product Details anti-TNFSF9 Antibody

Target: TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Rabbit

Clonality: Chimeric

Conjugate: This TNFSF9 antibody is un-conjugated

Application: Flow Cytometry (FACS), Blocking Reagent (BR)

Purpose: Anti-4-1BBL [TKS-1], Rabbit IgG, kappa

Specificity: This antibody binds to murine 4-1BBL and competes with binding of 4-1BB.

Characteristics:

Original Species of Ab: Rat

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogen: Murine B-cell lymphoma 2PK-3 cells injected into SD rats.

Clone: TKS-1

Isotype: IgG kappa

Application Details

Application Notes: This antibody has been used to detect 4-1BBL by flow cytometry. It is able to block 4-1BBL interacting with 4-1BB and prevent signalling.

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for TNFSF9

Target: TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))

Alternative Name: 4-1BBL (TNFSF9 Products)

Background: CD137L, TNFRSF9L, CD134 ligand, 4-1BB Ligand, TNFRSF9, TNFR superfamily 9, tumor necrosis factor receptor superfamily member 9

UniProt: P41274

Pathways: Activated T Cell Proliferation, Cancer Immune Checkpoints