Recombinant LTA antibody

Catalog No. ABIN7072399

Product Details anti-LTA Antibody

Target: LTA (Lymphotoxin-alpha (LTA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This LTA antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Neutralization (Neut), Surface Plasmon Resonance (SPR)

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG2b

Purification: Purified antibody.

Immunogen: 3F12 was prepared by hyperimmunizing BALB/c mice with purified recombinant human LTalpha expressed in E. coli - the hybridoma clone was selected for its ability to bind LTalpha3 by ELISA. The CDRs of the antibody were grafted to the framework regions of the mice mAb 2G7 to create the chimeric version of the antibody.

Clone: 3F12-2D3

Isotype: IgG kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for LTA

Target: LTA (Lymphotoxin-alpha (LTA))

Alternative Name: Lymphotoxin alpha (LTA Products)

Synonyms: LT antibody, TNFB antibody, TNFSF1 antibody, LT-[a] antibody, LT-alpha antibody, LT[a] antibody, LTalpha antibody, Ltx antibody, TNF-beta antibody, Tnfb antibody, Tnfsf1b antibody, hlb382 antibody, lymphotoxin alpha antibody, lymphotoxin A antibody, LTA antibody, Lta antibody

Target Type: Chemical

Background: LTα3 chimeric 3F12,LT, LTα, Tumor necrosis factor beta, Tumor necrosis factor β, Tumor necrosis factor-beta, tumor necrosis factor-β, TNF beta, TNF-beta, TNF β, TNF-β, Lymphotoxin-alpha, Lymphotoxin alpha

UniProt: P01374

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process