CRX antibody (AA 51-150)

Catalog No. ABIN704276

Product Details anti-CRX Antibody

Target: CRX (Cone-Rod Homeobox (CRX))

Binding Specificity: AA 51-150

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRX antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CRX

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CRX antibody (ABIN704276)

Machalińska, Rogińska, Pius-Sadowska, Kawa, Paczkowska, Rudnicki, Lejkowska, Baumert, Wiszniewska, Machaliński: "Neuroprotective and antiapoptotic activity of lineage-negative bone marrow cells after intravitreal injection in a mouse model of acute retinal injury." in: Stem cells international, Vol. 2015, pp. 620364, (2015) (PubMed).

Target Details for CRX

Target: CRX (Cone-Rod Homeobox (CRX))

Alternative Name: CRX1 (CRX Products)

Synonyms: Xotx5 antibody, Xotx5b antibody, cord2 antibody, crd antibody, otx5 antibody, otx5b antibody, rx antibody, CRX antibody, crx antibody, otx5-b antibody, CORD2 antibody, CRD antibody, LCA7 antibody, OTX3 antibody, Crx1 antibody, otx5-A antibody, cone-rod homeobox antibody, cone-rod homeobox L homeolog antibody, cone-rod homeobox S homeolog antibody, crx antibody, CRX antibody, Crx antibody, crx.L antibody, crx.S antibody

Background:

Synonyms: CRD, LCA7, OTX3, CORD2, Cone-rod homeobox protein, CRX

Background: Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.

Gene ID: 1406

UniProt: O43186