GM-CSF antibody (AA 65-144)

Catalog No. ABIN704156

Product Details anti-GM-CSF Antibody

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Binding Specificity: AA 65-144

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GM-CSF antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GM-CSF

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-GM-CSF antibody (ABIN704156)

Anzai, Choi, He, Fenn, Nairz, Rattik, McAlpine, Mindur, Chan, Iwamoto, Tricot, Wojtkiewicz, Weissleder, Libby, Nahrendorf, Stone, Becher, Swirski: "The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes." in: The Journal of experimental medicine, Vol. 214, Issue 11, pp. 3293-3310, (2017) (PubMed).

Hilgendorf, Theurl, Gerhardt, Robbins, Weber, Gonen, Iwamoto, Degousee, Holderried, Winter, Zirlik, Lin, Sukhova, Butany, Rubin, Witztum, Libby, Nahrendorf, Weissleder, Swirski: "Innate response activator B cells aggravate atherosclerosis by stimulating T helper-1 adaptive immunity." in: Circulation, Vol. 129, Issue 16, pp. 1677-87, (2014) (PubMed).

Xue, Chen, Cui, Cao, Zhou, Zheng, Gong: "Expression of hGM-CSF in silk glands of transgenic silkworms using gene targeting vector." in: Transgenic research, Vol. 21, Issue 1, pp. 101-11, (2012) (PubMed).

Target Details for GM-CSF

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Alternative Name: Gm-Csf (CSF2 Products)

Synonyms: GMCSF antibody, GM-CSF antibody, CSF2 antibody, Csfgm antibody, Gm-CSf antibody, MGI-IGM antibody, Gm-csf antibody, Gmcsf antibody, CSF antibody, colony stimulating factor 2 antibody, colony stimulating factor 2 (granulocyte-macrophage) antibody, CSF2 antibody, Csf2 antibody

Background:

Synonyms: Granulocyte-Macrophage Colony Stimulating Factor, Burst Promoting Activity, CMCSF, Colony Stimulating Factor 2, Colony stimulating factor, CSF 2, CSF Alpha, CSF, CSF2, Eosinophil Colony Stimulating Factor, GMCSF, Granulocyte Macrophage Colony Stimulating Factor, MGC131935, MGC138897, Molgramostin, Pluripoietin Alpha, Sargramostim, granulocyte-macrophage colony-stimulating factor precursor, CSF2_HUMAN.

Background: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.

Gene ID: 1437

UniProt: P04141

Pathways: JAK-STAT Signaling, Cellular Response to Molecule of Bacterial Origin