ADCY1 antibody (AA 751-850)

Catalog No. ABIN702565

Product Details anti-ADCY1 Antibody

Target: ADCY1 (Adenylate Cyclase 1 (Brain) (ADCY1))

Binding Specificity: AA 751-850

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Adenylyl cyclase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-ADCY1 antibody (ABIN702565)

Okamoto, Aung, Tanaka, Takeda, Takagi, Igarashi, Ishii, Yamakawa, Ono: "Preferential Expression of Ca2+-Stimulable Adenylyl Cyclase III in the Supraventricular Area, including Arrhythmogenic Pulmonary Vein of the Rat Heart." in: Biomolecules, Vol. 12, Issue 5, (2022) (PubMed).

Target Details for ADCY1

Target: ADCY1 (Adenylate Cyclase 1 (Brain) (ADCY1))

Alternative Name: ADCY1 (ADCY1 Products)

Synonyms: AC1 antibody, D11Bwg1392e antibody, I-AC antibody, brl antibody, mKIAA4070 antibody, Ac1 antibody, adenylate cyclase 1 antibody, adenylate cyclase type 1 antibody, adenylate cyclase 1 (brain) antibody, ADCY1 antibody, LOC100449504 antibody, adcy1 antibody, Adcy1 antibody

Background:

Synonyms: AC1, DFNB44, Adenylate cyclase type 1, ATP pyrophosphate-lyase 1, Adenylate cyclase type I, Adenylyl cyclase 1, Ca(2+)/calmodulin-activated adenylyl cyclase, ADCY1

Background: This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina (By similarity).

Gene ID: 107

UniProt: Q08828

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma