SRGAP3 antibody (AA 201-300)

Catalog No. ABIN702265

Product Details anti-SRGAP3 Antibody

Target: SRGAP3 (SLIT-ROBO rho GTPase Activating Protein 3 (SRGAP3))

Binding Specificity: AA 201-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRGAP3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human srGAP3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SRGAP3

Target: SRGAP3 (SLIT-ROBO rho GTPase Activating Protein 3 (SRGAP3))

Alternative Name: srGAP3 (SRGAP3 Products)

Background:

Synonyms: ARHGAP 14, ARHGAP14, Gbi, ME GAP, MEGAP, Mental disorder associated GAP, Rho GTPase activating protein 14, SLIT ROBO Rho GTPase activating protein 3, srGAP 2, srGAP 3, srGAP2, SRGP 2, SRGP2, WAVE associated Rac GTPase activating protein, WRP.

Background: srGAP3 (SLIT ROBO Rho GTPase-activating protein 3) is a GTPase activating protein (GAP) for the small G protein Rac. It has a putative role in attenuating Rac1 signalling in neurons. srGAP3 is thought to act downstream of the Slit-Robo pathway, which regulates neuronal migration and axonal branching, and play an important role in axonal regeneration after axotomy. It also plays a putative role in severe mental retardation.

Gene ID: 9901