DACH2 antibody (AA 501-599)

Catalog No. ABIN702250

Product Details anti-DACH2 Antibody

Target: DACH2 (Dachshund 2 (DACH2))

Binding Specificity: AA 501-599

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DACH2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DACH2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DACH2

Target: DACH2 (Dachshund 2 (DACH2))

Alternative Name: DACH2 (DACH2 Products)

Synonyms: 9430028N04Rik antibody, RGD1561687 antibody, dachshund family transcription factor 2 antibody, dachshund 2 (Drosophila) antibody, dachshund family transcription factor 2 L homeolog antibody, dachshund homolog 2 antibody, dachshund homolog 2 (Drosophila) antibody, DACH2 antibody, Dach2 antibody, dach2.L antibody, LOC612847 antibody, dach2 antibody

Background:

Synonyms: DACH 2, dachshund 2, Dachshund homolog 2 Drosophila, Dachshund homolog 2, Dachshund2, FLJ31391, HGNC:16814, MGC138545.

Background: DACH2 is a transcription factor that is involved in regulation of organogenesis. It seems to be a regulator for SIX1 and SIX6 and may act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. It probably binds to DNA via its DACH box-N domain.

Gene ID: 117154