FPR2 antibody (AA 51-150)

Catalog No. ABIN702175

Product Details anti-FPR2 Antibody

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Binding Specificity: AA 51-150

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Specificity: Possible cross-reactivity with FPR1

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FPRL1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-FPR2 antibody (ABIN702175)

Diao, Zhang, Chen, Yuan, Lee, Geng, Kowalski, Guo, Xiong, Li, Li: "Deficiency in Toll-interacting protein (Tollip) skews inflamed yet incompetent innate leukocytes in vivo during DSS-induced septic colitis." in: Scientific reports, Vol. 6, pp. 34672, (2016) (PubMed).

Target Details for FPR2

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Alternative Name: FPRL1/Lipoxin A4 receptor (FPR2 Products)

Synonyms: ALXR antibody, FMLP-R-II antibody, FMLPX antibody, FPR2A antibody, FPRH1 antibody, FPRH2 antibody, FPRL1 antibody, HM63 antibody, LXA4R antibody, E330010I07Rik antibody, Fpr-rs2 antibody, Fprl1 antibody, ALX antibody, Fpr-rs1 antibody, Fpr-s1 antibody, LXA4-R antibody, Lxa4r antibody, FMLP-R-I antibody, FPR2 antibody, formyl peptide receptor 2 antibody, formyl peptide receptor 3 antibody, N-formyl peptide receptor 2 antibody, FPR2 antibody, Fpr2 antibody, Fpr3 antibody, LOC100444626 antibody

Background:

Synonyms: ALXR, HM63, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, LXA4R, FMLP-R-II, N-formyl peptide receptor 2, FMLP-related receptor I, FMLP-R-I, Formyl peptide receptor-like 1, Lipoxin A4 receptor, LXA4 receptor, RFP, FPR2

Background: Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).

Gene ID: 2358

UniProt: P25090