PLEC antibody (AA 4451-4550) (Biotin)

Catalog No. ABIN701967

Product Details anti-PLEC Antibody (Biotin)

Target: PLEC (Plectin (PLEC))

Binding Specificity: AA 4451-4550

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLEC antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Plectin

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PLEC

Target: PLEC (Plectin (PLEC))

Alternative Name: Plectin (PLEC Products)

Background:

Synonyms: EBS1, EBSO, HD1, Hemidesmosomal protein 1, PCN, PLEC1, PLEC1b, Plectin 1 plectin 1 intermediate filament binding protein 500 kDa, Plectin 6, PLTN.

Background: Plectin interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the crosslinking and stabilization of cytoskeletal intermediate filaments network, but also in the regulation of their dynamics.