GPR77 antibody

Catalog No. ABIN7014008

Product Details anti-GPR77 Antibody

Target: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Reactivity: Human, Non-Human Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This GPR77 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Specificity: The mouse monoclonal antibody 1D9-M12 recognizes an extracellular epitope on C5aR2 (C5L2), a C5a complement receptor, which is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages.

Purification: Purified by protein-A affinity chromatography.

Immunogen: L1.2 cells transfected with human C5aR2

Clone: 1D9-M12

Isotype: IgG2a kappa

Application Details

Application Notes: Flow cytometry: Recommended dilution: 2-6 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for GPR77

Target: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Alternative Name: C5aR2 (GPR77 Products)

Synonyms: GPR77 antibody, C5L2 antibody, GPF77 antibody, E030029A11Rik antibody, Gpr77 antibody, complement component 5a receptor 2 antibody, C5AR2 antibody, C5ar2 antibody

Background: Complement component 5a receptor 2,C5aR2, also known as C5L2, is one of two receptors for C5a (anaphylatoxin). It is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages, and seems to have both pro-inflammatory and anti-inflammatory roles, depending on circumstances. Unlike CD88, C5aR2 is not coupled to G-protein, thus the modulatory role is more likely.,C5L2, GPR77, GPF77

Gene ID: 27202

UniProt: Q9P296