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- Target See all ITGA4 Antibodies
- ITGA4 (Integrin alpha 4 (ITGA4))
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This ITGA4 antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Specificity
- The rat monoclonal antibody R1-2 recognizes an extracellular epitope of murine CD49d / Integrin alpha 4 (VLA-4 alpha), an approximately 150 kDa glycoprotein of the integrin family, expressed on multiple blood cell types.
- Purification
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogen
- murine T lymphoma line TK1
- Clone
- R1-2
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product ITGA4 Primary Antibody
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anti-Integrin alpha 4 (ITGA4) (Internal Region) antibody
ITGA4 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha 4 (ITGA4) antibodyITGA4 Reactivity: Human FACS, WB, ELISA Host: Mouse Monoclonal 5C4 unconjugated
anti-Integrin alpha 4 (ITGA4) (AA 551-650) antibodyITGA4 Reactivity: Human, Mouse, Rabbit FACS, WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha 4 (ITGA4) (AA 833-977) antibodyITGA4 Reactivity: Human FACS, WB, ELISA Host: Mouse Monoclonal 7E4C5 unconjugated
anti-Integrin alpha 4 (ITGA4) (AA 376-558) antibodyITGA4 Reactivity: Human IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha 4 (ITGA4) antibodyITGA4 Reactivity: Human WB, IHC, IP Host: Rabbit Monoclonal unconjugated
anti-Integrin alpha 4 (ITGA4) (C-Term) antibodyITGA4 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha 4 (ITGA4) antibodyITGA4 Reactivity: Human FACS, WB, EIA Host: Mouse Monoclonal 5C4 unconjugated
anti-Integrin alpha 4 (ITGA4) antibodyITGA4 Reactivity: Mouse FACS, IP, IHC (fro) Host: Rat Monoclonal R1-2 unconjugated
anti-Integrin alpha 4 (ITGA4) antibodyITGA4 Reactivity: Mouse FACS, IP, IHC (fro) Host: Rat Monoclonal DATK32 unconjugated
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- Application Notes
- Flow cytometry: Recommended dilution: 1-5 μg/mL.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Target
- ITGA4 (Integrin alpha 4 (ITGA4))
- Alternative Name
- CD49d (ITGA4 Products)
- Synonyms
- CD49D antibody, IA4 antibody, LOC100219853 antibody, integrin subunit alpha 4 antibody, integrin alpha 4 antibody, integrin subunit alpha 4 S homeolog antibody, ITGA4 antibody, Itga4 antibody, itga4.S antibody
- Background
- Integrin subunit alpha 4,CD49d (integrin alpha 4), also known as very late antigen 4 alpha (VLA-4 alpha) is a cell surface glycoprotein constituting integrin complexes. CD49d heterodimerizes with CD29 (integrin beta 1) to form VLA-4 antigen, which is involved in cell-cell and cell-extracellular matrix interactions, which is a receptor for CD106 (VCAM) and fibronectin. CD79d also heterodimerizes with integrin beta 7 to form LPAM-1, which binds to MAdCAM-1 (mucosal vascular addressin). These interactions are important for cell adhesion and activation.,Itga4, Vla-4 alpha
- Gene ID
- 16401
- UniProt
- Q00651
- Pathways
- Integrin Complex
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