CD51/CD61 antibody
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- Target See all CD51/CD61 (ITGAV/ITGB3) Antibodies
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
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Reactivity
- Human, Chicken
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD51/CD61 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- The mouse monoclonal antibody 23C6 recognizes an extracellular epitope on CD51/CD61 complex, that is expressed mainly on human osteoclasts, but also e.g. on placenta, or melanoma cell lines. The epitope is native and sensitive to fixation. In chicken this antibody can be used to selectively identify the thrombocytes.
- No Cross-Reactivity
- Cow, Pig, Rabbit
- Purification
- Purified by protein-A affinity chromatography.
- Immunogen
- A cell suspension containing osteoclasts from osteoclastomas
- Clone
- 23C6
- Isotype
- IgG1
- Top Product
- Discover our top product ITGAV/ITGB3 Primary Antibody
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anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibody
ITGAV/ITGB3 Reactivity: Human, Mouse, Rat FACS, WB, IF (cc), IF (p), IHC (fro), ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibody (FITC)ITGAV/ITGB3 Reactivity: Human FACS, IHC Host: Mouse Monoclonal BV3 FITC
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibodyITGAV/ITGB3 Reactivity: Human, Chicken, Rabbit FACS, IHC, IHC (fro) Host: Mouse Monoclonal 23C6 unconjugated
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibody (PE)ITGAV/ITGB3 Reactivity: Human, Chicken FACS Host: Mouse Monoclonal 23C6 PE
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- Application Notes
- Flow cytometry: Recommended dilution: 2-6 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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- Target
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
- Alternative Name
- CD51/CD61 (ITGAV/ITGB3 Products)
- Synonyms
- CD51 antibody, MSK8 antibody, VNRA antibody, VTNR antibody, integrin subunit alpha V antibody, ITGAV antibody
- Background
- CD51/CD61 (integrin alpha5beta3), also known as osteoclast functional antigen, serves as a vitronectin receptor, and binds also to fibronectin, fibrinogen, thrombospondin, osteopontin, collagen, and von Willebrand factor. Expression of this antigen increases with melanoma progression. In healthy individuals CD51/CD61 is expressed mainly on osteoclasts, placenta, and endothelial cells, at lower levels on platelets and macrophages.,VNRA, MSK8, ITGB3, ITGAV, Integrin alpha5beta3, OFA, VR
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