Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

GZMB antibody (FITC)

GZMB Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal CLB-GB11 FITC
Catalog No. ABIN7013929
  • Target See all GZMB Antibodies
    GZMB (Granzyme B (GZMB))
    Reactivity
    • 125
    • 48
    • 24
    • 10
    • 3
    • 2
    • 1
    • 1
    Human, Non-Human Primate
    Host
    • 83
    • 44
    • 2
    Mouse
    Clonality
    • 81
    • 48
    Monoclonal
    Conjugate
    • 76
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GZMB antibody is conjugated to FITC
    Application
    • 71
    • 42
    • 38
    • 36
    • 18
    • 17
    • 16
    • 14
    • 13
    • 9
    • 9
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    The mouse monoclonal antibody CLB-GB11 recognizes granzyme B, a 31 kDa serine protease expressed intracellularly in activated Tc cells and NK cells.
    Purification
    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    Human NK cell line YT-INDY-derived granzyme B
    Clone
    CLB-GB11
    Isotype
    IgG1
    Top Product
    Discover our top product GZMB Primary Antibody
  • Application Notes
    Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Intracellular staining.
    Restrictions
    For Research Use only
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target
    GZMB (Granzyme B (GZMB))
    Alternative Name
    Granzyme B (GZMB Products)
    Synonyms
    CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody
    Background
    Granzyme B,Granzyme B is a serine protease that is expressed in cytoplasmic granules of cytotoxic T lymphocytes and NK cells. Vectorial secretion of perforin and granzymes is responsible for their granule-mediated cytotoxicity. Granzyme B plays a pivotal role in the induction of apoptosis in the target cells by activation of caspases. Moreover, granzyme B was reported to cleave directly alpha-tubulin, leading to perturbation of microtubule networks during the induced cell death.,GZMB, HLP, CTLA1, SECT
    Gene ID
    3002
    UniProt
    P10144
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis
You are here:
Support