HDAC6 antibody

Catalog No. ABIN7013923

Product Details anti-HDAC6 Antibody

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HDAC6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Specificity: The mouse monoclonal antibody 3D2 recognizes D2 domain of human histone deacetylase 6 (HDAC6, intracellular antigen), amino acids 471-481.

No Cross-Reactivity: Mouse, Zebrafish (Danio rerio)

Purification: Purified by protein-A affinity chromatography.

Immunogen: human HDAC6

Clone: 3D2

Isotype: IgG1 kappa

Application Details

Application Notes: Western blotting: Recommended dilution: 1-5 μg/mL.
Immunocytochemistry: Recommended dilution: 5-10 μg/mL.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for HDAC6

Target: HDAC6 (Histone Deacetylase 6 (HDAC6))

Alternative Name: HDAC6 (HDAC6 Products)

Synonyms: HD6 antibody, Hd6 antibody, Hdac5 antibody, Sfc6 antibody, mHDA2 antibody, CG6170 antibody, DHDAC2 antibody, DmHDAC2 antibody, Dmel\\CG6170 antibody, HDAC antibody, HDAC2 antibody, dHDAC2 antibody, dHDAC6 antibody, dmHDA404 antibody, hdac6 antibody, MGC53140 antibody, wu:fc31d02 antibody, dsim_GLEANR_17355 antibody, DsimGD17207 antibody, GD17207 antibody, HDAC6 antibody, ATHDA6 antibody, AXE1 antibody, HISTONE DEACETYLASE 6 antibody, MDC12.7 antibody, MDC12_7 antibody, RNA-MEDIATED TRANSCRIPTIONAL SILENCING 1 antibody, RPD3B antibody, RTS1 antibody, SIL1 antibody, histone deacetylase 6 antibody, histone deacetylase 6 antibody, Histone deacetylase 6 antibody, histone deacetylase 6 L homeolog antibody, GD17207 gene product from transcript GD17207-RB antibody, Histone DeAcetylase antibody, HDAC6 antibody, Hdac6 antibody, hdac6.L antibody, hdac6 antibody, Dsim\HDAC6 antibody, PTRG_03035 antibody, HDA6 antibody, hda-6 antibody

Background: Histone deacetylase 6,Histone deacetylase 6 (HDAC6), like other histone deacetylases, affects gene expression by regulation of chromatin remodeling. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. Besides histones, HDAC6 deacetylates also other substrates including alpha tubulin and HSP90 alpha, and is involved in protein trafficking and degradation, as well as in affecting of cell shape and migration. Deregulation of HDAC6 expression and activity is associated with many diseases.,Histone deacetylase 6

Gene ID: 10013

UniProt: Q9NSW6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling