IgE antibody (Biotin)
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- Target See all IgE Antibodies
- IgE
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IgE antibody is conjugated to Biotin
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Application
- ELISA, Flow Cytometry (FACS)
- Specificity
- The antibody BE5 reacts with human IgE, it recognizes an epitope different from the ones recognized by 4G7 and 4H10 antibodies to IgE.
- Purification
- Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
- Immunogen
- Purified human IgE.
- Clone
- BE5
- Isotype
- IgG1
- Top Product
- Discover our top product IgE Primary Antibody
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- Application Notes
- Flow cytometry: Recommended dilution: 1-12 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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- Target
- IgE
- Abstract
- IgE Products
- Synonyms
- IGH2 antibody, IgE antibody, Gm900 antibody, immunoglobulin heavy chain (epsilon polypeptide) antibody, immunoglobulin heavy constant epsilon antibody, Immunoglobulin heavy constant epsilon antibody, Ighe antibody, IGHE antibody
- Background
- Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.,Immunoglobulin E
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