SUSD2 antibody (APC)

Catalog No. ABIN7013897

Product Details anti-SUSD2 Antibody (APC)

Target: SUSD2 (Sushi Domain Containing 2 (SUSD2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SUSD2 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Specificity: The mouse monoclonal antibody W5C5 recognizes an extracellular epitope of SUSD2, a type I transmembrane protein expressed on mesenchymal stem-like cells. This antibody selectively binds to a MSCs in both bone marrow and endometrium or tonsil, and can be used for their identification and isolation.

Purification: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: WERI-RB-1 retinoblastoma cells

Clone: W5C5

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for SUSD2

Target: SUSD2 (Sushi Domain Containing 2 (SUSD2))

Alternative Name: SUSD2 (SUSD2 Products)

Synonyms: BK65A6.2 antibody, 1200011D11Rik antibody, sushi domain containing 2 antibody, SUSD2 antibody, Susd2 antibody

Background: Sushi domain containing 2,SUSD2 (sushi domain containing protein 2) is a type I transmembrane protein, that serves as an important marker of bone marrow-derived mesenchymal stem-like cells (bone marrow stromal cells). These pluripotent cells are important for techniques of autologous cell therapy, and can be collected from e.g. endometrium, or palatine tonsil. SUSD2 seems to be a tumor supresor, and is down-regulated in colon cancer tissues, whereas it is highly expressed e.g. in breast cancer.

Gene ID: 56241

UniProt: Q9UGT4