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TCR alpha/beta antibody
TCR alpha/beta
Reactivity: Rat, Non-Human Primate
FACS, IP, IHC (fro), WB, IHC (p), Func, ICC
Host: Mouse
Monoclonal
R73
unconjugated
Product Details anti-TCR alpha/beta Antibody
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Target
See all TCR alpha/beta products
TCR alpha/beta
(T Cell Receptor alpha/beta (TCR alpha/beta))
Reactivity
All reactivities for TCR alpha/beta antibodies
Rat, Non-Human Primate
Host
All hosts for TCR alpha/beta antibodies
Mouse
Clonality
All clonalities for TCR alpha/beta antibodies
Monoclonal
Conjugate
All conjugates for TCR alpha/beta antibodies
This TCR alpha/beta antibody is un-conjugated
Application
All applications for TCR alpha/beta antibodies
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func), Immunocytochemistry (ICC)
Specificity
The mouse monoclonal R73 recognizes an extracellular epitope TCR alpha/beta, the dominant subtype of T cell receptor expressed in peripheral blood.
Purification
Purified by protein-A affinity chromatography.
Endotoxin Level
Low Endotoxin
Immunogen
Rat T blasts and erythrocytes
Clone
R73
Isotype
IgG1 kappa
Alternatives
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Application Details
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Application Notes
Flow cytometry: Recommended dilution: 1-4 μg/mL. Functional application: In vitro activation and in vivo depletion of alpha/beta TCR T cells.
Restrictions
For Research Use only
Handling
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Concentration
1 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.4
Preservative
Azide free
Storage
4 °C
Storage Comment
Store at 2-8°C. Do not freeze.
Target Details for TCR alpha/beta
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Target
TCR alpha/beta
(T Cell Receptor alpha/beta (TCR alpha/beta))
Alternative Name
TCR alpha/beta (TCR alpha/beta Products )
Background
The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.,TCRA/B
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