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TCR alpha/beta antibody

TCR alpha/beta Reactivity: Rat, Non-Human Primate FACS, IP, IHC (fro), WB, IHC (p), Func, ICC Host: Mouse Monoclonal R73 unconjugated
Catalog No. ABIN7013895
  • Target See all TCR alpha/beta products
    TCR alpha/beta (T Cell Receptor alpha/beta (TCR alpha/beta))
    Reactivity
    • 14
    • 13
    • 9
    • 7
    • 6
    • 3
    • 3
    • 1
    Rat, Non-Human Primate
    Host
    • 30
    • 12
    Mouse
    Clonality
    • 42
    Monoclonal
    Conjugate
    • 14
    • 9
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    This TCR alpha/beta antibody is un-conjugated
    Application
    • 41
    • 26
    • 24
    • 18
    • 11
    • 7
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func), Immunocytochemistry (ICC)
    Specificity
    The mouse monoclonal R73 recognizes an extracellular epitope TCR alpha/beta, the dominant subtype of T cell receptor expressed in peripheral blood.
    Purification
    Purified by protein-A affinity chromatography.
    Endotoxin Level
    Low Endotoxin
    Immunogen
    Rat T blasts and erythrocytes
    Clone
    R73
    Isotype
    IgG1 kappa
  • Application Notes
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Functional application: In vitro activation and in vivo depletion of alpha/beta TCR T cells.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4
    Preservative
    Azide free
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    TCR alpha/beta (T Cell Receptor alpha/beta (TCR alpha/beta))
    Alternative Name
    TCR alpha/beta (TCR alpha/beta Products)
    Background
    The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.,TCRA/B
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