TRAFs and NIK-Associated Protein (TNAP) antibody
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- Target See all TRAFs and NIK-Associated Protein (TNAP) Antibodies
- TRAFs and NIK-Associated Protein (TNAP)
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Reactivity
- Human, Dog, Goat, Monkey, Pig, Sheep
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- Un-conjugated
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Application
- Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Specificity
- The mouse monoclonal antibody W8B2B10 recognizes TNAP (tissue non-specific alkaline phosphatase), an ectoenzyme expressed mainly on embryonic stem cells, liver, bone, and kidney cells. This antibody is suitable for characterization of bone marrow-derived MSCs, iPSCs, and ESCs.
- Purification
- Purified by protein-A affinity chromatography.
- Immunogen
- WERI-RB-1 retinoblastoma cell line
- Clone
- W8B2B10
- Isotype
- IgG1
- Top Product
- Discover our top product TNAP Primary Antibody
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- Application Notes
- Flow cytometry: Recommended dilution: 1-4 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Do not freeze.
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- Target
- TRAFs and NIK-Associated Protein (TNAP)
- Alternative Name
- TNAP (TNAP Products)
- Synonyms
- AP-TNAP antibody, APTNAP antibody, HOPS antibody, TNAP antibody, TNSALP antibody, Akp-2 antibody, Akp2 antibody, alkaline phosphatase, liver/bone/kidney antibody, ALPL antibody, Alpl antibody
- Background
- Alkaline phosphatase, biomineralization associated,Tissue non-specific alkaline phosphatase (TNAP), also known as liver/bone/kidney alkaline phosphatase, or MSCA-1 (mesenchymal stem cell antigen 1) is a selective marker for the prospective isolation of bone marrow-derived mesenchymal stem cells and mesenchymal stem-like cells. It is expressed at high levels in liver, bone, kidney, or endometrium, as well as on embryonic stem cells (ESCs). TNAP also plays a role in bone mineralization. Mutations in TNAP gene are associated with hypercalcemia and skeletal defects (hypophosphatasia).,Tissue Non-specific Alkaline Phosphatase, MSCA-1, liver/bone/kidney alkaline phosphatase
- Gene ID
- 249
- UniProt
- P05186
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