Raptor antibody (pSer792)

Catalog No. ABIN7265290

Product Details anti-Raptor Antibody

Target: Raptor (RPTOR) (Regulatory Associated Protein of mTOR, Complex 1 (RPTOR))

Binding Specificity: pSer792

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Raptor antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Phosphorylated antibody

Purification: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding Ser792 of human RPTOR

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Raptor

Target: Raptor (RPTOR) (Regulatory Associated Protein of mTOR, Complex 1 (RPTOR))

Alternative Name: RPTOR (RPTOR Products)

Synonyms: KOG1 antibody, Mip1 antibody, 4932417H02Rik antibody, Rap antibody, Raptor antibody, mKIAA1303 antibody, RGD1311784 antibody, raptor antibody, regulatory associated protein of MTOR complex 1 antibody, regulatory associated protein of MTOR, complex 1 antibody, regulatory associated protein of MTOR, complex 1 L homeolog antibody, RPTOR antibody, Rptor antibody, rptor.L antibody, rptor antibody

Background: This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID: 57521

UniProt: Q8N122

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Autophagy, BCR Signaling, Warburg Effect