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RPS6KB1 antibody (pThr389)

RPS6KB1 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7265266
  • Target See all RPS6KB1 Antibodies
    RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
    Binding Specificity
    • 21
    • 20
    • 20
    • 19
    • 18
    • 16
    • 16
    • 15
    • 15
    • 15
    • 15
    • 15
    • 14
    • 14
    • 10
    • 8
    • 8
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr389
    Reactivity
    • 317
    • 227
    • 224
    • 56
    • 24
    • 21
    • 20
    • 17
    • 12
    • 9
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 298
    • 33
    • 3
    • 2
    Rabbit
    Clonality
    • 299
    • 37
    Polyclonal
    Conjugate
    • 164
    • 19
    • 16
    • 14
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    This RPS6KB1 antibody is un-conjugated
    Application
    • 279
    • 134
    • 104
    • 92
    • 91
    • 71
    • 61
    • 31
    • 24
    • 18
    • 17
    • 8
    • 7
    • 4
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Phosphorylated antibody
    Purification
    Affinity purification
    Immunogen
    A phospho specific peptide corresponding to residues surrounding T389 of human P70 S6K
    Isotype
    IgG
    Top Product
    Discover our top product RPS6KB1 Primary Antibody
  • Application Notes
    IHC 1:50-1:200 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
    Alternative Name
    P70 S6K (RPS6KB1 Products)
    Background
    This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.
    Gene ID
    6198
    UniProt
    P23443
    Pathways
    PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Cell Size, Skeletal Muscle Fiber Development, Feeding Behaviour, G-protein mediated Events, Smooth Muscle Cell Migration, Interaction of EGFR with phospholipase C-gamma, Warburg Effect
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