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RPS6KB1 antibody (pThr389)
RPS6KB1
Reactivity: Human, Mouse, Rat
IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RPS6KB1 Antibody
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Target
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RPS6KB1
(Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
Binding Specificity
All epitopes for RPS6KB1 antibodies
pThr389
Reactivity
All reactivities for RPS6KB1 antibodies
Human, Mouse, Rat
Host
All hosts for RPS6KB1 antibodies
Rabbit
Clonality
All clonalities for RPS6KB1 antibodies
Polyclonal
Conjugate
All conjugates for RPS6KB1 antibodies
This RPS6KB1 antibody is un-conjugated
Application
All applications for RPS6KB1 antibodies
Immunohistochemistry (IHC), Immunofluorescence (IF)
Characteristics
Phosphorylated antibody
Purification
Affinity purification
Immunogen
A phospho specific peptide corresponding to residues surrounding T389 of human P70 S6K
Isotype
IgG
Top Product
Discover our top product RPS6KB1 Primary Antibody
Alternatives
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anti-Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) (pThr389), (pThr412) antibody
RPS6KB1
Reactivity: Human, Mouse, Rat, Pig
WB, IHC, ELISA, IF, ICC
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
IHC 1:50-1:200 IF 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for RPS6KB1
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Target
RPS6KB1
(Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))
Alternative Name
P70 S6K (RPS6KB1 Products )
Background
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.
Gene ID
6198
UniProt
P23443
Pathways
PI3K-Akt Signaling , RTK Signaling , AMPK Signaling , Regulation of Cell Size , Skeletal Muscle Fiber Development , Feeding Behaviour , G-protein mediated Events , Smooth Muscle Cell Migration , Interaction of EGFR with phospholipase C-gamma , Warburg Effect
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