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beta Catenin antibody (pSer33, pSer37, pThr41)

CATNB Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7265240
  • Target See all beta Catenin (CATNB) Antibodies
    beta Catenin (CATNB) (Catenin, beta (CATNB))
    Binding Specificity
    • 48
    • 27
    • 25
    • 25
    • 23
    • 19
    • 17
    • 17
    • 16
    • 16
    • 16
    • 15
    • 10
    • 8
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer33, pSer37, pThr41
    Reactivity
    • 343
    • 254
    • 231
    • 27
    • 23
    • 22
    • 18
    • 16
    • 7
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 286
    • 57
    • 4
    • 1
    • 1
    Rabbit
    Clonality
    • 279
    • 70
    Polyclonal
    Conjugate
    • 130
    • 22
    • 11
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    This beta Catenin antibody is un-conjugated
    Application
    • 214
    • 159
    • 120
    • 118
    • 80
    • 63
    • 62
    • 52
    • 34
    • 32
    • 24
    • 9
    • 7
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    Phosphorylated antibody
    Purification
    Affinity purification
    Immunogen
    A synthetic phosphorylated peptide around S33 & T41 of human beta Catenin (NP_001091679).
    Isotype
    IgG
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  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    beta Catenin (CATNB) (Catenin, beta (CATNB))
    Alternative Name
    beta-catenin (CATNB Products)
    Synonyms
    Bfc antibody, Catnb antibody, Mesc antibody, CTNNB antibody, MRD19 antibody, armadillo antibody, ctnnb antibody, id:ibd2058 antibody, wu:fb73e10 antibody, wu:fi81c06 antibody, wu:fk25h01 antibody, beta-catenin antibody, ctnnb1 antibody, CHBCAT antibody, catenin (cadherin associated protein), beta 1 antibody, catenin beta 1 antibody, catenin (cadherin-associated protein), beta 1 antibody, catenin beta 1 L homeolog antibody, Ctnnb1 antibody, CTNNB1 antibody, ctnnb1 antibody, ctnnb1.L antibody
    Background
    The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.
    Molecular Weight

    Observed_MW: 85 kDa

    Calculated_MW: 9 kDa/85 kDa

    Gene ID
    1499
    UniProt
    P35222
    Pathways
    Peptide Hormone Metabolism
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