×
For best experience we recommend to activate Javascript in your browser.
Separase antibody (pSer1126)
ESPL1
Reactivity: Human
IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Separase Antibody
(hide)
Target
See all Separase (ESPL1) Antibodies
Separase (ESPL1)
(Extra Spindle Poles Like 1 (ESPL1))
Binding Specificity
All epitopes for Separase antibodies
pSer1126
Reactivity
All reactivities for Separase antibodies
Human
Host
All hosts for Separase antibodies
Rabbit
Clonality
All clonalities for Separase antibodies
Polyclonal
Conjugate
All conjugates for Separase antibodies
This Separase antibody is un-conjugated
Application
All applications for Separase antibodies
Immunofluorescence (IF)
Characteristics
Phosphorylated antibody
Purification
Affinity purification
Immunogen
A synthetic phosphorylated peptide around S1126 of human ESPL1 (NP_036423.4).
Isotype
IgG
Top Product
Discover our top product ESPL1 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
IF 1:20-1:100
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for Separase
(hide)
Target
Separase (ESPL1)
(Extra Spindle Poles Like 1 (ESPL1))
Alternative Name
ESPL1 (ESPL1 Products )
Background
Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids.
Gene ID
9700
UniProt
Q14674
Recently viewed
(hide)