IGF1R antibody (pTyr1161)
-
- Target See all IGF1R Antibodies
- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
-
Binding Specificity
- pTyr1161
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This IGF1R antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Characteristics
- Phosphorylated antibody
- Purification
- Affinity purification
- Immunogen
- A phospho specific peptide corresponding to residues surrounding Y1161 of human IGF1R
- Isotype
- IgG
- Top Product
- Discover our top product IGF1R Primary Antibody
-
-
- Application Notes
- WB 1:500-1:2000 IHC 1:50-1:100 IF 1:100-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
- Alternative Name
- IGF1R (IGF1R Products)
- Background
- This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
- Molecular Weight
-
Observed_MW: 95 kDa
Calculated_MW: 154 kDa
- Gene ID
- 3480
- UniProt
- P08069
- Pathways
- RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
-