Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

IGF1R antibody (pTyr1161)

IGF1R Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7265182
  • Target See all IGF1R Antibodies
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    Binding Specificity
    • 23
    • 23
    • 19
    • 14
    • 12
    • 12
    • 11
    • 10
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr1161
    Reactivity
    • 189
    • 109
    • 92
    • 16
    • 8
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 174
    • 29
    • 2
    • 1
    Rabbit
    Clonality
    • 176
    • 30
    Polyclonal
    Conjugate
    • 127
    • 8
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    This IGF1R antibody is un-conjugated
    Application
    • 133
    • 72
    • 60
    • 60
    • 33
    • 25
    • 18
    • 13
    • 13
    • 11
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Phosphorylated antibody
    Purification
    Affinity purification
    Immunogen
    A phospho specific peptide corresponding to residues surrounding Y1161 of human IGF1R
    Isotype
    IgG
    Top Product
    Discover our top product IGF1R Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:100 IF 1:100-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    Alternative Name
    IGF1R (IGF1R Products)
    Background
    This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Molecular Weight

    Observed_MW: 95 kDa

    Calculated_MW: 154 kDa

    Gene ID
    3480
    UniProt
    P08069
    Pathways
    RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
You are here:
Support