Paxillin antibody (pTyr118)
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- Target See all Paxillin (PXN) Antibodies
- Paxillin (PXN)
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Binding Specificity
- pTyr118
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Paxillin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Phosphorylated antibody
- Purification
- Affinity purification
- Immunogen
- A phospho specific peptide corresponding to residues surrounding Y118 of human PXN
- Isotype
- IgG
- Top Product
- Discover our top product PXN Primary Antibody
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- Application Notes
- WB 1:500-1:2000 IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Paxillin (PXN)
- Alternative Name
- PXN (PXN Products)
- Background
- This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445).
- Molecular Weight
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Observed_MW: 70 kDa
Calculated_MW: 46 kDa/60 kDa/64 kDa/66 kDa
- Gene ID
- 5829
- UniProt
- P49023
- Pathways
- MAPK Signaling, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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