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c-MYC antibody (pSer62)

MYC Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7265076
  • Target See all c-MYC (MYC) Antibodies
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    Binding Specificity
    • 58
    • 49
    • 46
    • 40
    • 24
    • 22
    • 17
    • 15
    • 15
    • 14
    • 10
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer62
    Reactivity
    • 360
    • 164
    • 117
    • 16
    • 15
    • 13
    • 13
    • 13
    • 10
    • 10
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 279
    • 98
    • 7
    • 5
    • 3
    • 1
    Rabbit
    Clonality
    • 273
    • 119
    Polyclonal
    Conjugate
    • 191
    • 31
    • 24
    • 23
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This c-MYC antibody is un-conjugated
    Application
    • 288
    • 139
    • 96
    • 80
    • 76
    • 58
    • 56
    • 28
    • 26
    • 21
    • 16
    • 14
    • 12
    • 11
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Phosphorylated antibody
    Purification
    Affinity purification
    Immunogen
    A phospho specific peptide corresponding to residues surrounding S62 of human MYC
    Isotype
    IgG
    Top Product
    Discover our top product MYC Primary Antibody
  • Application Notes
    IHC 1:50-1:200 IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    Alternative Name
    MYC (MYC Products)
    Background
    The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
    Gene ID
    4609
    UniProt
    P01106
    Pathways
    p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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