CDK1 antibody (pTyr15)
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- Target See all CDK1 Antibodies
- CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
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Binding Specificity
- pTyr15
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDK1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Characteristics
- Phosphorylated antibody
- Purification
- Affinity purification
- Immunogen
- A synthetic phosphorylated peptide around Y15 of human CDK1 (NP_001777.1).
- Isotype
- IgG
- Top Product
- Discover our top product CDK1 Primary Antibody
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- Application Notes
- WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
- Alternative Name
- CDK1 (CDK1 Products)
- Background
- The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
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Observed_MW: 34 kDa
Calculated_MW: 27 kDa/34 kDa
- Gene ID
- 983
- UniProt
- P06493
- Pathways
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
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