Fibulin 5 antibody
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- Target See all Fibulin 5 (FBLN5) Antibodies
- Fibulin 5 (FBLN5)
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Fibulin 5 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human FBLN5 (NP_006320.2).
- Isotype
- IgG
- Top Product
- Discover our top product FBLN5 Primary Antibody
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- Application Notes
- WB 1:500-1:2000 IF 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Fibulin 5 (FBLN5)
- Alternative Name
- FBLN5 (FBLN5 Products)
- Background
- The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).
- Molecular Weight
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Observed_MW: 72 kDa
Calculated_MW: 50 kDa
- Gene ID
- 10516
- UniProt
- Q9UBX5
- Pathways
- SARS-CoV-2 Protein Interactome
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