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Fibulin 5 antibody

FBLN5 Reactivity: Human, Mouse WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7264982
  • Target See all Fibulin 5 (FBLN5) Antibodies
    Fibulin 5 (FBLN5)
    Reactivity
    • 59
    • 33
    • 28
    • 1
    Human, Mouse
    Host
    • 57
    • 6
    • 1
    Rabbit
    Clonality
    • 57
    • 9
    Polyclonal
    Conjugate
    • 27
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Fibulin 5 antibody is un-conjugated
    Application
    • 47
    • 25
    • 13
    • 5
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human FBLN5 (NP_006320.2).
    Isotype
    IgG
    Top Product
    Discover our top product FBLN5 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Fibulin 5 (FBLN5)
    Alternative Name
    FBLN5 (FBLN5 Products)
    Background
    The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).
    Molecular Weight

    Observed_MW: 72 kDa

    Calculated_MW: 50 kDa

    Gene ID
    10516
    UniProt
    Q9UBX5
    Pathways
    SARS-CoV-2 Protein Interactome
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