SEC31A antibody
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- Target See all SEC31A Antibodies
- SEC31A (SEC31 Homolog A (SEC31A))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SEC31A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human SEC31A (NP_055748.2).
- Isotype
- IgG
- Top Product
- Discover our top product SEC31A Primary Antibody
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- Application Notes
- WB 1:1000-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- SEC31A (SEC31 Homolog A (SEC31A))
- Alternative Name
- SEC31A (SEC31A Products)
- Synonyms
- ABP125 antibody, ABP130 antibody, HSPC334 antibody, SEC31L1 antibody, Sec31l1 antibody, VAP1 antibody, 1810024J13Rik antibody, AU042160 antibody, HSPC275 antibody, cb354 antibody, sec31p antibody, zgc:63547 antibody, SEC31 homolog A, COPII coat complex component antibody, Sec31 homolog A (S. cerevisiae) antibody, SEC31A antibody, Sec31a antibody, sec31a antibody
- Background
- The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molecular Weight
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Observed_MW: 165 kDa
Calculated_MW: 56 kDa/105-134 kDa
- Gene ID
- 22872
- UniProt
- O94979
- Pathways
- ER-Nucleus Signaling
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