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SEC31A antibody

SEC31A Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7264783
  • Target See all SEC31A Antibodies
    SEC31A (SEC31 Homolog A (SEC31A))
    Reactivity
    • 29
    • 12
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 22
    • 8
    Rabbit
    Clonality
    • 22
    • 8
    Polyclonal
    Conjugate
    • 14
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SEC31A antibody is un-conjugated
    Application
    • 17
    • 12
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human SEC31A (NP_055748.2).
    Isotype
    IgG
    Top Product
    Discover our top product SEC31A Primary Antibody
  • Application Notes
    WB 1:1000-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SEC31A (SEC31 Homolog A (SEC31A))
    Alternative Name
    SEC31A (SEC31A Products)
    Synonyms
    ABP125 antibody, ABP130 antibody, HSPC334 antibody, SEC31L1 antibody, Sec31l1 antibody, VAP1 antibody, 1810024J13Rik antibody, AU042160 antibody, HSPC275 antibody, cb354 antibody, sec31p antibody, zgc:63547 antibody, SEC31 homolog A, COPII coat complex component antibody, Sec31 homolog A (S. cerevisiae) antibody, SEC31A antibody, Sec31a antibody, sec31a antibody
    Background
    The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Molecular Weight

    Observed_MW: 165 kDa

    Calculated_MW: 56 kDa/105-134 kDa

    Gene ID
    22872
    UniProt
    O94979
    Pathways
    ER-Nucleus Signaling
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