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OCRL antibody

OCRL Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7264779
  • Target See all OCRL Antibodies
    OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))
    Reactivity
    • 27
    • 11
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 21
    • 6
    Rabbit
    Clonality
    • 24
    • 3
    Polyclonal
    Conjugate
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OCRL antibody is un-conjugated
    Application
    • 15
    • 11
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human OCRL (NP_001578.2).
    Isotype
    IgG
    Top Product
    Discover our top product OCRL Primary Antibody
  • Application Notes
    WB 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))
    Alternative Name
    OCRL (OCRL Products)
    Synonyms
    OCRL antibody, wu:fi09g03 antibody, zgc:152864 antibody, locr antibody, nphl2 antibody, ocrl1 antibody, inpp5f antibody, INPP5F antibody, LOCR antibody, NPHL2 antibody, OCRL-1 antibody, OCRL1 antibody, 9530014D17Rik antibody, BB143339 antibody, OCRL, inositol polyphosphate-5-phosphatase antibody, phosphatidylinositol polyphosphate 5-phosphatase antibody, oculocerebrorenal syndrome of Lowe antibody, Ocrl antibody, NAEGRDRAFT_58601 antibody, OCRL antibody, ocrl antibody
    Background
    This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.
    Molecular Weight

    Observed_MW: 110 kDa

    Calculated_MW: 103 kDa/104 kDa

    Gene ID
    4952
    UniProt
    Q01968
    Pathways
    Inositol Metabolic Process
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