OCRL antibody
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- Target See all OCRL Antibodies
- OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This OCRL antibody is un-conjugated
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Application
- Western Blotting (WB)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human OCRL (NP_001578.2).
- Isotype
- IgG
- Top Product
- Discover our top product OCRL Primary Antibody
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- Application Notes
- WB 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))
- Alternative Name
- OCRL (OCRL Products)
- Synonyms
- OCRL antibody, wu:fi09g03 antibody, zgc:152864 antibody, locr antibody, nphl2 antibody, ocrl1 antibody, inpp5f antibody, INPP5F antibody, LOCR antibody, NPHL2 antibody, OCRL-1 antibody, OCRL1 antibody, 9530014D17Rik antibody, BB143339 antibody, OCRL, inositol polyphosphate-5-phosphatase antibody, phosphatidylinositol polyphosphate 5-phosphatase antibody, oculocerebrorenal syndrome of Lowe antibody, Ocrl antibody, NAEGRDRAFT_58601 antibody, OCRL antibody, ocrl antibody
- Background
- This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.
- Molecular Weight
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Observed_MW: 110 kDa
Calculated_MW: 103 kDa/104 kDa
- Gene ID
- 4952
- UniProt
- Q01968
- Pathways
- Inositol Metabolic Process
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