HBa2 antibody

Catalog No. ABIN7264463

Product Details anti-HBa2 Antibody

Target: HBa2 (Hemoglobin, alpha 2 (HBa2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBa2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human HBA2 (NP_000508.1).

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HBa2

Target: HBa2 (Hemoglobin, alpha 2 (HBa2))

Alternative Name: HBA2 (HBa2 Products)

Synonyms: HBAM antibody, Hba-a1 antibody, Hba-a2 antibody, hba2 antibody, HBH antibody, hba5 antibody, HBA2 antibody, alpha globin antibody, HBA1 antibody, HBAI antibody, HBAII antibody, Glnc1 antibody, GloA antibody, hemoglobin, alpha 1 antibody, hemoglobin subunit alpha 1 S homeolog antibody, hemoglobin subunit alpha 2 antibody, hemoglobin subunit alpha 2 L homeolog antibody, hemoglobin subunit mu antibody, hemoglobin, alpha 2 antibody, hemoglobin subunit alpha-2-like antibody, hemoglobin alpha, adult chain 1 antibody, hemoglobin alpha, adult chain 2 antibody, Hba1 antibody, hba1.S antibody, HBA2 antibody, hba2.L antibody, HBM antibody, HBA antibody, Hba2 antibody, LOC102168959 antibody, Hba-a1 antibody, Hba-a2 antibody

Background: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97 % of the total hemoglobin, alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3 % of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1, some nondeletion alpha thalassemias have also been reported.

Gene ID: 3040

UniProt: P69905