gabpa-A antibody, XrpFI antibody, X-alpha1 antibody, GABPA antibody, nft2 antibody, nrf2 antibody, nrf2a antibody, e4tf1a antibody, e4tf1-60 antibody, Nrf-2alpha antibody, Nrf2a antibody, E4TF1-60 antibody, E4TF1A antibody, NFT2 antibody, NRF2 antibody, NRF2A antibody, RCH04A07 antibody, GABPalpha antibody, e4tf antibody, wu:fc12d11 antibody, GA binding protein transcription factor alpha subunit S homeolog antibody, GA binding protein transcription factor alpha subunit antibody, GA binding protein transcription factor, alpha subunit antibody, GA binding protein transcription factor alpha subunit L homeolog antibody, GA repeat binding protein, alpha antibody, gabpa.S antibody, GABPA antibody, gabpa antibody, Gabpa antibody, gabpa.L antibody
Background
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.